publications

2025

  1. lumi-lab.gif
    LUMI-lab: a foundation model-driven autonomous platform enabling discovery of new ionizable lipid designs for mRNA delivery
    Haotian Cui**, Yue Xu**, Kuan Pang*, Gen Li*, Fanglin Gong*, Bo Wang†, and Bowen Li†
    Accepted at Cell, 2025
    PDF
  2. pulsar.gif
    PULSAR: a Foundation Model for Multi-scale and Multicellular Biology
    Kuan Pang*, Yanay Rosen*, Kasia Kedzierska, Ziyuan He, Abhe Rajagopal, Claire E Gustafson, Grace Huynh, and Jure Leskovec†
    bioRxiv, 2025
    PDF

2024

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    Spatially Resolved Gene Expression Prediction from Histology Images via Bi-modal Contrastive Learning
    Ronald Xie, Kuan Pang, Sai Chung, Catia Perciani, Sonya MacParland, Bo Wang†, and Gary Bader†
    Advances in Neural Information Processing Systems, 2024
    PDF
  2. scgpt.gif
    scGPT: toward building a foundation model for single-cell multi-omics using generative AI
    Haotian Cui*, Chloe Wang*, Hassaan Maan, Kuan Pang, Fengning Luo, Nan Duan, and Bo Wang
    Nature Methods, 2024
    PDF

2023

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    MAESTER: Masked Autoencoder Guided Segmentation at Pixel Resolution for Accurate, Self-Supervised Subcellular Structure Recognition
    Ronald Xie*, Kuan Pang*, Gary D Bader†, and Bo Wang†
    In Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, 2023
    ✨Selected as Highlight(top2.5%)✨
    PDF